Nano therapeutic scaffold for wound care and pain management: A make in India Aatmanirbhar Bharat Initiative of PDEU

 Authors: Prof. Dr. S. Sundar Manoharan; Dr. Sivaraman Dhanasekaran; Dr. P. S. Pradeep

The PDEU team has made significant advancements in nano-therapeutic scaffolds for pain and wound management, contributing to the Make in India and Aatmanirbhar Bharat initiatives. Key innovations include Penta Nanoplast, a transdermal patch for muscle pain management that addresses the limitations of oral medications and conventional bandages by ensuring rapid drug release and enhanced patient compliance. Knew Nanoplast, a nano-coated knee wrap, optimizes drug delivery around joint cartilage, reducing pain, inflammation, and swelling while improving joint flexibility. In wound care, NanoHyFi, a hydrofiber-based dressing, combines nanotechnology driven antibiotics with a gel-forming fiber to deliver drugs and restrict germ entry, accelerating healing for surgical wounds. Similarly, Nanosol demonstrates exceptional efficacy against multi-drug-resistant pathogens in burn wound healing, ensuring scar-free recovery and matching the original skin tone. Supported by the Ministry of Education under the STARS scheme, Nanosol is being further explored for treating diabetic foot ulcers. The most recent breakthrough, TINAENS, a drug-loaded nanoscaffold-based dressing, targets drug-resistant Staphylococcus aureus and has received patent recognition, marking a milestone in infection control. All these products are in the TRL 6-7 stage, pending commercialization. One of these innovation “Knew Nanoplast” was selected for presentation at the DHR-ICMR Health Research Excellence Recognition Summit 2024 under best innovation category. The health care innovations were showcased during a technical briefing to Dr. Mukesh Ambani, President and Chairman of the PDEU Board of Governance, on January 10, 2024, and previously presented to FDCA authorities on December 18, 2021. These cutting-edge nanotechnologies provide cost-effective, efficient solutions to address critical healthcare challenges, including pain, inflammation, and wound care, with a focus on improving patient outcomes and reducing medical costs.

Technical Briefing to Dr. Mukesh Ambani (10th January 2024)

Healthcare Innovation Showcase at ICMR Summit 2024 – 14^th Nov 2024 - Dr Rajiv Bahl , Director General, Indian Council of Medical Research (ICMR)

Product Display for FDCA Authorities (18th December 2021): Pre Vibrant Gujarat Summit Holistic Healthcare